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The focus of free-standing cancer hospitals is specifically on providing comprehensive cancer treatment and care. These facilities are dedicated exclusively to oncology, meaning they are designed to offer specialized services tailored to the treatment of cancer patients. This includes a range of services such as chemotherapy, radiation therapy, surgery, and support programs specifically for cancer care.

In contrast, critical access hospitals, sole community hospitals, and rural referral centers can provide a variety of medical services, but they do not specialize exclusively in cancer treatment. For instance, critical access hospitals are intended to serve rural communities with essential health services, while sole community hospitals serve as a critical provider for areas with limited healthcare facilities. Rural referral centers typically provide more advanced care and may include specialty services, but they are not exclusively focused on cancer treatment. This distinction sets free-standing cancer hospitals apart as the facility type that solely concentrates on cancer-related healthcare.